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Visiting Professorship in Pennsylvania
Dr. Reynolds visits Penn State Milton S. Hershey Medical Center
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Groups Reaffirm Position on Use of Vaginal Mesh for Surgical Treatment of Stress Urinary Incontinence
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2017 SUFU Research Foundation Resident Preceptorship
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Announcing the SUFU Visiting Professorship
This 1-day visiting professorship will be offered to interested training programs and will consist of a lecture series from a member of the SUFU Executive Committee encompassing all aspects of FPMRS, Urodynamics, and Neurourology.
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Diokno-Lapides Essay Contest
Announcing the Diokno-Lapides Essay Contest is NOW OPEN to all physicians, PhD scientists, and MD and PhD trainees throughout the world! ...
SUNA Core Curriculum for Urologic Nursing
The first edition of the SUNA Core Curriculum for Urologic Nursing is now available. This comprehensive publication is an excellent resource for all urologic nurses....
ICS-SUFU Early Career promotion
ICS now offers a special reduced rate for SUFU early career professionals. For just £40 you can become an ICS early career professional member! ...
FDA Reclassification of Surgical Instrumentation
As anticipated, the FDA reclassified the surgical instrumentation for use with urogynecological surgical mesh from class I (general controls) to class II (special controls) effective January 6, 2017. ...
Neurourology and Urodynamics
The fabrication of 3D surface scaffold of collagen/poly (L‐lactide‐co‐caprolactone) with dynamic liquid system and its application in urinary incontinence treatment as a tissu...
Monday, October 23, 2017
Aims To fabricate a novel nanoyarn biomaterial via a dynamic liquid electrospinning system, and to simultaneously evaluate whether nanoyarn is capable of being applied as a urinary sling for future clinical transfer. Methods Nanoyarn was cultured with adipose‐derived stem cells (ADSCs). Cell morphology and function were observed on nanoyarn. Female rats that underwent vagina dilatation (VD) and bilateral ovarian resection (BOR) were used as the urinary incontinence model. After 2 weeks, the cells‐sling was fixed to the suburethra. A commercial sling that tension‐free vaginal tape‐obturator (TVT‐O) was used as a control. The urodynamic test for leak point pressure (LPP) and histological tests were used to evaluate the sling's performance in vivo. Results The nanoyarn possessed beneficial properties and the actin filament from ADSCs, which is very similar to muscle. Rats that underwent VD and BOR maintained a low LPP, whereas the LPP in rats with VD alone recovered to normal levels within 2 weeks. LPP in the nanoyarn group gradually decreased on the three urodynamic tests post‐suburethral surgery, however, the cell‐laden nanoyarn maintained LPP at normal levels for 8 weeks; the TVT‐O group showed a significant increase in LPP at 8 weeks. Cell‐laden nanoyarn was infiltrated with more cells, collagen, and vessels than the controls. Conclusions The nanoyarn showed sufficient efficacy to maintain LPP in urinary incontinence rat model. In addition, it improved cell infiltration, collagen and muscle development compared to TVT‐O. Thus, the combination of ADSCs and a nanoyarn scaffold could be a promising tissue‐engineered sling for the treatment of urinary incontinence.
Anterior colporrhaphy plus inside‐out tension‐free vaginal tape for associated stress urinary incontinence and cystocele: 10‐year follow up results
Monday, October 23, 2017
Aims We report the success rate and complications rate of combined ultralateral anterior Colporrhaphy plus Tension‐free Vaginal Tape (TVT‐O) in a long‐term (10 year) follow‐up prospective survey. Methods Patients previously treated for associated stress urinary incontinence (SUI) and cystocele were subjected to annual follow‐up for 10 year with a complete urogynecologic evaluation. Furthermore, an urodynamic assessment and a quality of life questionnaire (ICIQ‐UI SF) were recorded at the 5th and 10th year of follow up. Results Fifty patients treated between June 2004 and May 2006 were included in the analysis. Five patients did not return to 5‐yr follow‐up: two patients developed a median tape erosion and three patients withdraw. At 10‐yr follow‐up two more patients withdraw for a total of seven patients lost to follow‐up. After 10 years patients objectively cured from cystocele were 41 (95%) while patients objectively cured from SUI were 39 (91%). At 10th year follow‐up 38 patients (89%) result cured from both SUI and cystocele, 3 (7%) patients result cured only from prolapse, 1 (2%) patient only from SUI, and 1 (2%) patient result objectively failed for both SUI and cystocele. The ICIQ‐UI SF scores at 10th year follow‐up was 6.2 ± 3.7. The late complication rate at 10th year follow‐up was 32% (OAB symptoms 20%; Mixed incontinence 2%; Bladder outlet obstruction 0%; Dyspareunia 6%; Chronic pelvic pain 0%; Vaginal tape erosion 4%; Detrusor hyperactivity 0%). Conclusions The combined procedures shown proved to be an effective and safe procedure to treat concomitant SUI and cystocele.
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